Our scopes were designed specifically for sedation-free Transnasal Endoscopy (TNE), making it the ideal solution to comply with the 2025 ACG guidelines. Because your child's healthcare experience matters, the EvoEndo Endoscopy System improves the lives of patients, families, and healthcare professionals. Our devices meet the ACG guidelines for sedation-free TNE—because we do it for the kids.

From the ACG Guidelines:

“Over the past decade, there have been paradigm shifts in disease diagnosis and management... and development of validated outcome metrics.”

 

“The assessment of mucosal inflammation requires the use of endoscopic techniques with sedation in those who are not able to receive the unsedated transnasal approach described above.”

 

“Unsedated transnasal endoscopy is
now used, particularly in children, to
minimize anesthesia exposure and costs. It is safe, well tolerated, and can provide the endoscopic and histologic measures (EREFS and esophageal biopsies) to
assess response.”

For follow-up and monitoring of EoE, unsedated transnasal endoscopy (TNE) is now the recommended form of endoscopy in children and is to be highly considered in adults. This guideline change reduces anesthesia exposure and costs. TNE is well tolerated and provides reliable histologic and endoscopic assessments.

Supporting Guideline Quotes:

“The assessment of mucosal inflammation requires the use of endoscopic techniques with sedation in those who are not able to receive the unsedated transnasal approach described above.”

EvoEndo devices are the preferred alternative to traditional sedated procedures, offering a safer option for pediatric patients. EvoEndo’s technology provides a sedation-free procedure that allows for regular monitoring while being minimally invasive and eliminating the risks associated with sedation.

Supporting Guideline Quotes:

“The assessment of mucosal inflammation requires the use of endoscopic techniques with sedation in those who are not able to receive the unsedated transnasal approach described above.”

“Currently, response assessment in EoE relies on endoscopy with biopsies; although there are no noninvasive biomarkers that have been validated to assess response, several less- or minimally invasive techniques are available.”

Sedation-free TNE helps providers detect disease progression earlier, enabling timely intervention and better patient outcomes.

Supporting Guideline Quote:

“EoE progresses from an inflammatory to a fibrostenotic phenotype in most, but not all, patients.”

EvoEndo technology enables providers to offer an efficient, safe, and preferred method of monitoring EoE. It facilitates more informative follow-up visits that are more convenient and less time-consuming. The EvoEndo Model LE scope provides the recommended and preferred visualization and biopsy of the entire esophagus.

Supporting Guideline Quotes:

“Monitoring with clinical, endoscopic, and histologic assessments is recommended to assess for treatment response and follow patients over time with maintenance therapy.”

“A careful endoscopic examination is mandatory for all suspected esophageal diseases, and for EoE, this includes taking substantial time to visualize the entire esophagus.”

EvoEndo technology provides sedation-free Transnasal Endoscopy (TNE), which allows for regular, minimally invasive monitoring without the risks associated with sedation. By enabling more frequent assessments, it helps providers detect disease progression earlier, enabling timely intervention and better patient outcomes.

Supporting Guideline Quote:

“EoE progresses from an inflammatory to a fibrostenotic phenotype in most, but not all, patients.”

EvoEndo’s Model LE Gastroscopes capture HD images that facilitate accurate EREFS scoring, reinforcing its clinical utility in the routine monitoring of EoE patients.

Supporting Guideline Quote:

“A critical aspect of the examination is assessing EoE findings using the EREFS, a recommendation also endorsed by recent guidelines by the American Society for Gastrointestinal Endoscopy (ASGE).”

Our scope can pass through strictures more easily than traditional endoscopes, allowing a physician to visualize both sides of the stricture before intervening. EvoEndo technology also allows for multiple biopsies to be obtained easily and efficiently during a physician visit without the need for needles or anesthesia.

Supporting Guideline Quotes:

“A key point when approaching esophageal dilation is to recognize that detection of esophageal strictures in EoE can be difficult on endoscopic examination.”

“We recommend obtaining at least 6 esophageal biopsies from at least 2 esophageal levels (e.g., proximal/mid and distal), targeting EoE endoscopic findings, if possible, to assess for histologic features consistent with EoE.”

EvoEndo’s Model LE Gastroscopes capture HD images that facilitate accurate EREFS scoring, reinforcing its clinical utility in the routine monitoring of EoE patients.

Supporting Guideline Quote:

“A critical aspect of the examination is assessing EoE findings using the EREFS, a recommendation also endorsed by recent guidelines by the American Society for Gastrointestinal Endoscopy (ASGE).”

Our scope can pass through strictures more easily than traditional endoscopes, allowing a physician to visualize both sides of the stricture before intervening.

Supporting Guideline Quote:

“A key point when approaching esophageal dilation is to recognize that detection of esophageal strictures in EoE can be difficult on endoscopic examination.”

EvoEndo technology allows for multiple biopsies to be obtained easily and efficiently during a physician visit without the need for needles or anesthesia.

Supporting Guideline Quote:

“We recommend obtaining at least 6 esophageal biopsies from at least 2 esophageal levels (e.g., proximal/mid and distal), targeting EoE endoscopic findings, if possible, to assess for histologic features consistent with EoE.”