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New ACG Guidelines for EoE

The American College of Gastroenterology (ACG) provides evidence-based recommendations for diagnosing and managing various gastrointestinal and liver diseases, helping clinicians make informed decisions and improve patient care. 

The latest 2025 ACG guidelines for Eosinophilic Esophagitis (EoE) mark a shift toward safer, more accessible care — especially for pediatric patients.

EvoEndo applauds ACG for its updated guidance, and we are proud that our technology aligns with these evolving standards of care.

Learn more about ACG
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    ACG Eosinophilic Esophagitis Clinical Guidelines

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EoE Highlights

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Complete Guidelines 

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Apfed Response

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    Key Highlights 

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Sedation-Free TNE

Sedation-free TNE is a safer and better-tolerated alternative to minimize anesthesia exposure and healthcare costs.

Patient Safety

With a focus on patient safety and concerns over risks of repeated sedation, TNE is preferred, particularly when treatments pose risks.

Continuing Care

Sedation-free TNE is recommended for regular endoscopic assessments, response monitoring, and long-term maintenance therapy.

Visualization & Biopsy

Slim, flexible scopes used during TNE provide enhanced visualization and efficient biopsy collection without sedation or anesthesia.

EREFS Scoring

The EREFS standardized scoring system is recommended for endoscopic assessments, including TNE for esophageal biopsies.

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Managing EoE: Early Detection Is Critical

Eosinophilic Esophagitis (EoE) can silently progress without clear symptoms, making regular esophageal assessment essential. Sedation-free transnasal endoscopy offers improved and safer access to endoscopic evaluations when recommended by your physician or healthcare provider.

Risk factors for EoE progression include:

  • Poor symptom correlation with active inflammation

  • Undetected stricture formation

  • Progressive esophageal narrowing


The EvoEndo® Endoscopy System supports proactive, sedation-free assessment and monitoring.

 

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Why Sedation-Free TNE?

Watch Dr. Yamen Smadi at Orlando Health Arnold Palmer Hospital for Children (2:21–3:15) explain why sedation-free transnasal endoscopy (TNE) is a great option for patients with Eosinophilic Esophagitis (EoE).

Clinical Data and Research
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